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Demodex granuloma - Scar - Skin

Y Rosen, MD & P Meseguer, MD posted a photo:

Demodex granuloma - Scar - Skin

Demodex folliculorum is a microscopic mite that can survive only on the skin of humans. Most people (90%) have D. folliculorum on their skin. Demodex folliculorum measures 0.3 to 0.4 mm long. Adults have four pairs of legs; larvae and nymphs have only three pairs. The entire life cycle of Demodex takes 14–16 days. Adult mites copulate at the top of the hair follicle, near the skin surface. Eggs are deposited in the sebaceous gland inside the hair follicle. The heart-shaped egg is 0.1 mm long, and hatches into a six-legged larva. In seven days the larva develops into a mature adult, with two intervening nymph stages.
Usually, the mites do not cause any harm, so are considered an example of commensalism rather than parasitism; but they can cause disease, known as demodicosis when they grow excessively.
In the present case, the mite has been exposed to the host's immune system when the follicle that contained it ruptured due to a wound. You can see scarring fibrosis on top and an inflammatory reaction with macrophage lymphocytes and giant cells around the arthropod.
These mites have nocturnal habits, moving up to 16 mm/h, making very intimate contact necessary for transmission between people. It is believed that the main transmission is from mother to child during breastfeeding.
The term Demodex is derived from the Greek words, "demo" (lard) and "dex" (boring worm) to describe the preferred shape and location of this organism.

Images contributed by Dr. Pascual Meseguer - @Histopatolomon

Other photos of Demodex folliculorum can be seen in this Atlas.

Sun, 14 Jul 2024 11:38:42 -0700
demodex demodexfolliculorum exogenous foreignbodies foreignbodyexogenous foreignbody microscopic skin scar granuloma
Iron pill aspiration - Ferrous sulfate - Bronchus

Y Rosen, MD & P Meseguer, MD posted a photo:

Iron pill aspiration - Ferrous sulfate - Bronchus

Ferrous sulfate (FeSO4) tablets are used to combat anemia, being one of the most widely used medications. It is estimated that roughly 7% of all foreign bodies aspirated into the airways are medicinal pills. They may be found whole or as small or large fragments. Here we see fragments of the pill, which have a golden-crystalline and fibrilar structure. Smaller granules, probably already metabolized, are present. Some may be located within macrophages or giant cells. it has been suggested that the iron pill fragments resemble Gamna-Gandy bodies.
This material is strongly stained with an iron stain (Perls Prussian blue stain), as can be seen in the in the photo above on the right. The long, thin granules, if they are the only finding, can be mistaken for ferruginous bodies.

Images contributed by Dr. Sanjay Mukhopadhyay - @smlungpathguy

Wed, 10 Jul 2024 11:18:44 -0700
aspiration microscopic bronchialaspiration bronchus bronchoscopy feso4 ferroussulfate foreiegnbody ironpill ironpillaspiration iron pills exogenous pigment foreignbody

In the heart of nature

PanzerSniper54 posted a photo:

In the heart of nature

I've taken a close-up photo, and I find it very interesting because of its diversity and the beautiful light.

Sun, 07 Jul 2024 13:51:56 -0700
light microscopic nature earth trefoil greenary soil plant grass
starlord

landaofu1891 posted a photo:

starlord

number 1

Thu, 04 Jul 2024 00:50:00 -0700
star diatom microscopic

Turmeric and unidentified FB's - Skin wound

Y Rosen, MD & P Meseguer, MD posted a photo:

Turmeric and unidentified FB's - Skin wound

These images show two or possibly three types of foreign bodies that were found below a fragment of basal cell carcinoma in a biopsy specimen obtained from a facial ulcer. The large, ovoid, bluish structures that contain coiled material are typical of turmeric. The other foreign bodies are not identified but may be materials that were mixed with the turmeric.
Turmeric is a common spice that comes from the root of Curcuma longa. It contains a chemical called curcumin, which might reduce swelling. Because curcumin and other chemicals in turmeric might decrease swelling, it is often used to treat conditions that involve pain and inflammation. Turmeric powder may contain other ingredients including Bioperine, an extract derived from black pepper, ginger root, black pepper, and cinnamon. It’s possible that the unidentified foreign bodies may be one or more of these extra ingredients.
Turmeric has a microscopic resemblance to hydrophilic polymers which are widely used as surface coatings on vascular medical devices including guidewires, introducer and delivery sheaths, implantable stents and coils as well as cardiac, central and peripheral catheters. However, the fragments of hydrophilic polymer are smaller than those of turmeric.

Images contributed by Dr. Apoorva Pandit - @PanditApoorva

Mon, 24 Jun 2024 12:51:44 -0700
foreignbody exogenous turmeric undetermined microscopic skin
Japanese Beetles Mating - 2x Macro

tuomikoskig posted a photo:

Japanese Beetles Mating - 2x Macro

Found in a bush.

Sun, 23 Jun 2024 19:47:25 -0700
wildlife insect macro macroscopic microscopic tiny closeup nature

Undetermined crystalline FB - Stomach

Y Rosen, MD & P Meseguer, MD posted a photo:

Undetermined crystalline FB - Stomach

These birefringent crystals are present in a stomach biopsy with x-ray/reparative changes. These crystals are present in all levels of the tissue. Its origin has not been proven. They do not seem to be crystals produced by the patient. It seems possible that they are from a tablet that contains resin, and also that it could be an artifact/contaminant,

Images contributed by Dr. Dan Graham - @DanGrahamMD

Sun, 23 Jun 2024 02:36:51 -0700
stomach microscopic foreignbody crystals undetermined undeterminedforeignbody birefringent
Aluminum/Aluminium-vaccination associated - Skin

Y Rosen, MD & P Meseguer, MD posted a photo:

Aluminum/Aluminium-vaccination associated - Skin

Aluminum/ Aluminium is used as an adjuvant in vaccinations to improve their effectiveness. Aluminium/Aluminium can sometimes cause a delayed hypersensitivity response (i.e. granulomatous reaction) at the injection sites. Common injection sites are the upper arm and thigh. A good history can helpful in recognizing this lesion. Typical findings seen in these images are plump epithelioid histiocytes not quite forming granulomas and fine fragments of bluish granular material in histocytes. The granular material is PAS positive (not shown).

Images contributed by Dr. Tristan Rutland MBBS FRCPA IFCAP

Sat, 22 Jun 2024 11:39:57 -0700
foreignbody aluminum vaccination skin microscopic adjuvant injection aluminium histiocytes

Macro of the Eye of a Needle

tuomikoskig posted a photo:

Macro of the Eye of a Needle

Shot on a Fujifilm X-T5 with a Laowa 2x 100mm and a Raynox DCR-250 diopter.

Fri, 14 Jun 2024 13:34:40 -0700
macro macroscopic closeup tiny object microscopic
Diacetyl

chemicalbull0 posted a photo:

Diacetyl

Diacetyl is a chemical compound with a buttery flavor and aroma, commonly found in dairy products and used as a flavoring agent in foods like popcorn and margarine.

Wed, 12 Jun 2024 03:18:03 -0700
3d virus cell background bacteria antivirus render life genetic medical microbe biology science close organs microbiology cancer health drug macro blood surface human experiment sickness microcosmic vein flow organic disease infection sick medicine microscopic scientific illustration

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